PathMD Quizes, Breast Breast – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. All the following are direct or obligate precursors to breast carcinoma EXCEPT:Sclerosing adenosisComplex sclerosing lesionPapillomaRadial scar 2. All of the following are positive in pseudo-angiomatous stromal hyperplasia EXCEPT:CD34All the answers are positiveVimentinCD31Actin 3. During pregnancy a 36-year-old female noted an enlarging breast mass 4 cm in greatest dimension. A FNA was performed and representative cytologic images are shown. Based on these findings, what is the best diagnosis? Breast - Part 1, Question #2 Breast - Part 1, Question #2FibroadenomaMedullary carcinoma LymphomaNone of the answers are correctInvasive breast cancer 4. After fibroadenoma, what is the most common focal mass lesion of the breast?DCISSclerosing adenosisFibrocystic Disease Phyllodes tumor Papilloma 5. The malignant cells and Paget's disease may stain with all of the following EXCEPT:ER/PRPASHigh molecular weight cytokeratinsCEAEMA 6. All the following are associated with fibromatosis of the breast EXCEPT:Neurofibromatosis type 1 PregnancyTraumaGardner syndrome 7. In a phyllodes tumor the breast, what is the usual mitotic rate found in a borderline tumor?5-10 mitoses/10 hpf <10 mitoses/10 hpf 10-<20 mitoses/50 hpf 5-10 mitoses/50 hpf 10-20 mitoses/10 hpf 8. An irregular breast mass was found on self examination by a 46-year-old female. A FNA was performed and representative images are shown for this case, which highlight cells with atypical cytology that are discohesive and in a clean background. What is the best diagnosis? Breast - Part 1, Question #1 Breast - Part 1, Question #1 Breast - Part 1, Question #1FibroadenomaLymphomaNone of the answers are correctMedullary carcinoma Invasive breast cancer 9. Multiple masses are noted in the breast of a 40-year-old female. To reassure the patient, an excision was performed and a representative image of the histology is shown. Based on these findings, what is the best diagnosis? Breast - Part 1, Question #3None of the answers are correctApocrine carcinomaElongated a lobular units with columnar cell alteration (ELUCA) Fibrocystic changesDuctal carcinoma in situ with apocrine change 10. All the following are true with regards to fibroadenomas EXCEPT:The most common mass lesion in the breast Most common in women in their 20s-30s Are differentiated from fibroadenomatoid hyperplasia by the presence of a capsuleMore common in Afro-Caribbean women Loading...