1. Which of the following is not true of drug metabolism:

2. A 33-year-old jaundiced man is found to have the following serum laboratory values: Total Bilirubin of 3.0 mg/dL (normal <1.0), Direct bilirubin of 2.7 mg/dL (normal <0.2).  Which of the following is the most likely cause?

3. Macroamylase refers to:

4. Warfarin metabolism is mainly performed by:

5. Which of the following is the most specific serum marker for alcohol dependency?

6. A 52-year-old man with a history of alcohol abuse presents with sudden severe abdominal pain associated with nausea and vomiting. Which of the following is true when considering serum testing for acute pancreatitis?

7. A 63-year-old woman with weight loss is found to have a slightly elevated alanine aminotransferase level of 45 U/L (N=8-33 U/L) and an elevated aspartate aminotransferase level of 150 U/L (N=4-36 U/L).  Which of the following is the most likely cause?

8. An active form of an antidepressant is subsequently oxidized by P450 CYP2C9. Which patients would you generally expect to need the highest dose of antidepressants to maintain similar serum concentrations of active drug?

9. Which of the following is untrue in cases of toxic overdose of acetaminophen?

10. A 53-year-old woman presents with chronic intermittent acute abdominal pain that is determined to stem from common bile duct obstruction. Which of the following liver function markers would one not expect to be highly elevated in the serum?