PathMD Quizes, Clinical, Hematopathology Coagulation – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped. Which of the following tests would be most helpful in diagnosing the patient?Qualitative d-dimer ADAM-TS level Heparin antibody Methyltetrahydrofolate reductase mutationQuantitative d-dimer 2. Adhesion of platelets is mediated through all of the following EXCEPT:CollagenGPIbvon Willebrand's factorGPIIb/IIIa 3. Which of the following would be least helpful in treating a patient with hemophilia A:FFPDDAVPCryoprecipitateRecombinant factor VIIIAll of the answers would be helpful 4. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image? Coagulation - Part 1, Question #2CollagenVon Willebrands factor GPIIb/IIIa receptor GPIb receptor Fibrinogen 5. A patient is suspected of having Bernard-Soulier disease. If the patient has this disease, they would show response to all of the following during platelet testing EXCEPT:CollagenThromboxane A2ADPEpinephrineRistocetin 6. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped. The most likely etiology is:HyperhomocystinemiaHeparin induced thrombocytopeniaIdiopathic Thrombocytopenia purpuraThrombotic thrombocytopeniaDVT with paradoxical embolus 7. The PFA-100 analyzer has replaced the bleeding time at many institutions. This test utilizes two tubes for analysis. One tube contains collagen and ADP, while the other tube has collagen epinephrine. In a patient who has a prolonged bleeding time, which of the following would have a normal clotting time in the collagen and ADP tube but be prolonged and the collagen epinephrine tube?Aspirin effectThrombocytopeniaBernard-Soulier disease Von Willebrand's disease All the answers will affect both tubes 8. A patient who is known to have von Willebrand’s disease (vWD) has a normal vWF antigen and decreased levels of Factor VIII. What is the most likely vWD subtype in this patient?vWD, type 2M vWD, type 2N vWD, type 2B vWD, type 2A Platelet type, pseudo-von Willebrand’s disease 9. Moderate hemophilia A is characterized by which of the following approximated factor VIII levels:>20%1-5% 10-20% <1%5-10% 10. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image? Coagulation - Part 1, Question #1CollagenGPIIb/IIIa receptor FibrinogenGPIb receptor Von Willebrands factor Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related