1. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped.

Which of the following tests would be most helpful in diagnosing the patient?

2. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image?

3. A patient underwent cardiac bypass surgery and was having an uneventful post-operative course. On POD #7, the patient developed an ischemic leg. The intern asks your help in diagnosis, and also informs you that his platelet count has recently dropped. The most likely etiology is:

4. A patient who is known to have von Willebrand’s disease (vWD) has a normal vWF antigen and decreased levels of Factor VIII. What is the most likely vWD subtype in this patient?

5. The PFA-100 analyzer has replaced the bleeding time at many institutions. This test utilizes two tubes for analysis. One tube contains collagen and ADP, while the other tube has collagen epinephrine. In a patient who has a prolonged bleeding time, which of the following would have a normal clotting time in the collagen and ADP tube but be prolonged and the collagen epinephrine tube?

6. A patient is suspected of having Bernard-Soulier disease. If the patient has this disease, they would show response to all of the following during platelet testing EXCEPT:

7. Which of the following would be least helpful in treating a patient with hemophilia A:

8. Moderate hemophilia A is characterized by which of the following approximated factor VIII levels:

9. Adhesion of platelets is mediated through all of the following EXCEPT:

10. The image for this question shown on the website represents initial platelet adhesion to the vessel wall and aggregation. What structure is represented by the red box in the image?