PathMD Quizes, Clinical Endocrine Pathology – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?t(2;5)t(8;14)t(11;14)t(14;18) 2. Where in the normal thyroid gland are C-cells found in the highest concentration?Upper poleLower poleMiddle portionIsthmus 3. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis? Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1Follicular carcinomaFollicular adenomaFollicular variant of papillary carcinomaNodular hyperplasiaAdenomatoid nodules 4. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:Microinvasive follicular carcinomas have an excellent prognosisRadiation exposure is a risk factorPropensity for lymphatic invasionHigher incidence in iodine deficient areasRepresent ~5% of thyroid cancers 5. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis? Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASAcinar cell cystadenomaEpithelioid angiosarcomaMicrocystic serous cystadenomaLymphangiomaPancreatic pseudocyst 6. What is the fatality rate for widely invasive follicular carcinoma tumors?75%3%>90%25%50% 7. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. This entity can be associated with all of the following EXCEPT: Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASVon Hippel-Lindau diseaseDuctal adenocarcinoma of the pancreasDiabetesMultiple endocrine neoplasia 8. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. Chromogranin Endocrine-Exocrine, Question #9. SynaptophysinAdrenal carcinomaPheochromocytomaMyelolipomaAdrenal cortical adenoma 9. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5. CD3. Endocrine-Exocrine, Question #5. CD5. Endocrine-Exocrine, Question #5. CD20. Endocrine-Exocrine, Question #5. BCL-1. Endocrine-Exocrine, Question #5. BCL-2.Marginal zone lymphomaMantle cell lymphomaDiffuse large B-cell lymphomaAtypical reactive lymphoid hyperplasiaCLL/SLL 10. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. SynaptophysinCarneyʼs syndromeVon Hippel-Lindau diseaseCarneyʼs triadMultiple endocrine neoplasiaNone of the answers are correct Loading... Share this:TwitterWhatsAppFacebookEmailPrintLinkedIn Related