PathMD Quizes, Clinical Endocrine Pathology – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5. CD3. Endocrine-Exocrine, Question #5. CD5. Endocrine-Exocrine, Question #5. CD20. Endocrine-Exocrine, Question #5. BCL-1. Endocrine-Exocrine, Question #5. BCL-2.Diffuse large B-cell lymphomaAtypical reactive lymphoid hyperplasiaMarginal zone lymphomaCLL/SLLMantle cell lymphoma 2. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?t(11;14)t(14;18)t(8;14)t(2;5) 3. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis? Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1Follicular variant of papillary carcinomaFollicular adenomaFollicular carcinomaAdenomatoid nodulesNodular hyperplasia 4. Where in the normal thyroid gland are C-cells found in the highest concentration?IsthmusMiddle portionUpper poleLower pole 5. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. Chromogranin Endocrine-Exocrine, Question #9. SynaptophysinMyelolipomaAdrenal cortical adenomaPheochromocytomaAdrenal carcinoma 6. What is the fatality rate for widely invasive follicular carcinoma tumors?3%25%75%>90%50% 7. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:Microinvasive follicular carcinomas have an excellent prognosisRadiation exposure is a risk factorHigher incidence in iodine deficient areasRepresent ~5% of thyroid cancersPropensity for lymphatic invasion 8. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis? Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASEpithelioid angiosarcomaPancreatic pseudocystMicrocystic serous cystadenomaLymphangiomaAcinar cell cystadenoma 9. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. This entity can be associated with all of the following EXCEPT: Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASMultiple endocrine neoplasiaDuctal adenocarcinoma of the pancreasDiabetesVon Hippel-Lindau disease 10. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. SynaptophysinNone of the answers are correctCarneyʼs syndromeMultiple endocrine neoplasiaCarneyʼs triadVon Hippel-Lindau disease Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related