PathMD Quizes, Clinical Endocrine Pathology – 01 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Where in the normal thyroid gland are C-cells found in the highest concentration?Middle portionLower poleUpper poleIsthmus 2. What is the fatality rate for widely invasive follicular carcinoma tumors?25%3%75%50%>90% 3. All of the following are true with respect to follicular thyroid carcinoma EXCEPT:Higher incidence in iodine deficient areasRadiation exposure is a risk factorMicroinvasive follicular carcinomas have an excellent prognosisPropensity for lymphatic invasionRepresent ~5% of thyroid cancers 4. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. Based on the histology and special stains, what is the best diagnosis? Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASEpithelioid angiosarcomaLymphangiomaMicrocystic serous cystadenomaAcinar cell cystadenomaPancreatic pseudocyst 5. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. Chromogranin Endocrine-Exocrine, Question #9. SynaptophysinAdrenal carcinomaPheochromocytomaAdrenal cortical adenomaMyelolipoma 6. A 42 y/o female presents with a 10 cm pancreatic head mass. A CT guided biopsy is performed, which was noted to be very bloody during the procedure and on touch preparation. This entity can be associated with all of the following EXCEPT: Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7 Endocrine-Exocrine, Question #7. AE1/AE3 Endocrine-Exocrine, Question #7. CD34 Endocrine-Exocrine, Question #7. PASMultiple endocrine neoplasiaVon Hippel-Lindau diseaseDiabetesDuctal adenocarcinoma of the pancreas 7. A 60 y/o man undergoes colonoscopy, and is noted to have a “nodular” mucosal surface. Multiple biopsies are performed, and representative images and stains are shown. Based on the findings, what is the best diagnosis? Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5 Endocrine-Exocrine, Question #5. CD3. Endocrine-Exocrine, Question #5. CD5. Endocrine-Exocrine, Question #5. CD20. Endocrine-Exocrine, Question #5. BCL-1. Endocrine-Exocrine, Question #5. BCL-2.CLL/SLLAtypical reactive lymphoid hyperplasiaDiffuse large B-cell lymphomaMantle cell lymphomaMarginal zone lymphoma 8. In mantle cell lymphoma, which of the following FISH studies would most likely be positive?t(8;14)t(2;5)t(11;14)t(14;18) 9. A patient is found to have an adrenal mass. The adrenal gland is removed, and representative histologic images are shown. The patient in the above case was found to have a gastric stromal sarcoma. In light of the new findings, what is the best clinical diagnosis for this patient? Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9 Endocrine-Exocrine, Question #9. SynaptophysinNone of the answers are correctCarneyʼs syndromeVon Hippel-Lindau diseaseCarneyʼs triadMultiple endocrine neoplasia 10. A 50 y/o male presents with an enlarged thyroid. Due to the mass effect, a complete thyroidectomy is performed. Based on the images shown, what is the best diagnosis? Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1 Endocrine-Exocrine, Question #1Follicular carcinomaAdenomatoid nodulesFollicular adenomaNodular hyperplasiaFollicular variant of papillary carcinoma Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related