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Organ Systems, Gynecological, Uterus

Endometrial Serous (High Grade) Carcinoma

October 10, 2017 peferguson
High-grade tumor of the uterus with the following IHC characteristics:
 
p53
Often positive, and usually negative in endometrioid carcinoma.
CK7
Positive
CA125
Positive
p16
Positive
Ki-67
Usually high proliferation index
Vimentin
Positive
CK20
Negative
ER
Negative (may see low level expression)
CEA
Negative

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