1. Mantle Cell Lymphoma is associated with which of the following:

2. A patient presents with an elevated WBC count, and flow cytometry is performed. Based on the dot plots shown the website images for this case, what is the best diagnosis?

3. A 40 year old woman presents with an elevated WBC count (25K) with abnormal immature cells noted by the hematology technologist (see case images). Flow cytometry demonstrated the cells to be positive for CD13 and CD33 and negative for CD34 and HLA-DR. What is the best diagnosis?

4. A 36 year old Hispanic male with a CD4 count of 20 presents to the emergency department complaining of chronic headaches for several months. A routine CBC showed pancytopenia, and a bone marrow biopsy was performed. Based on the findings, what is the most likely diagnosis?

5. All of the following are true with respect to MALT/marginal zone lymphomas EXCEPT:

6. A patient with a history of acute leukemia undergoes a bone marrow aspiration. Part of the specimen is sent for cytogenetic analysis. Results of the karyotype are shown in the image for this case. Based on the findings (which are highlighted by red arrows), what is the best diagnosis?

7. Which of the following chromosomal abnormalities is commonly found in multiple myeloma:

8. A patient presents with an elevated WBC count, and flow cytometry is performed. Based on the dot plots shown on the website images for this case, what is the best diagnosis?

9. A 12 year old boy presents with a WBC of 233K. The bone marrow aspirate with a myeloperoxidase stain are shown. Flow cytometry demonstrated CD19 positivity. What is the best diagnosis?

10. Which of the following are associated with a worse prognosis in CLL/SLL: