Lysozyme (LZ) is similar to myeloperoxidase (MPO) in that they are associated with cytoplasmic bactericidal granules, which are specific for myeloid differentiation. LZ is most useful along with other markers such as MPO and CD117 in identifying case of AML, in which none of the markers are entirely sensitive.
References
Bone Marrow IHC. Torlakovic, EE, et. al. American Society for Clinical Pathology Pathology Press © 2009. pp.161.