1. For a test with a Gaussian distribution, what is the minimum number of representative samples needed to determine a reference range?

2. Of the series of numbers { 1,3,3,3,4,5,5,7,8 }, calculate the mode, median, and mean, respectively.

3. The coefficient of variation best represents which of the following:

4. A new instrument is installed for CBCs, and a correlation test is performed. The reference method is plotted on the X-axis and the new method on the Y-axis for multiple samples tested. Linear regression analysis is performed (y=mx + b). Which of the following represents the correlation coefficient, r?

5. A series of data for a new clinical lab test has a Gaussian distribution. What percent of the data will be more than 3 standard deviations above the mean?

6. Which of the following correlation coefficients (r) represents the minimal number you would like to see when validating a new test?

7. To validate a previously established reference range, what is the minimal number of healthy person samples needed?

8. Of the following answers, which is the best tool to detect bias between two different methods?

9. For a test without a Gaussian distribution, what is the minimal number of representative samples needed to establish a reference range?

10. If 20 tests were performed on a “healthy” individual, what is the likelihood all of the results will be within the reference range?