PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAnti-thyroid peroxidase antibodiesAnti-thyroglobulin antibodiesIt may present as an enlarging thyroid glandAntibodies to the TSH receptor 2. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Increase the dose of L-thyroxineObservation and thyroid studies at 24 weeksDiscontinue L-thyroxineMeasure the T4 concentrationDecrease the dose of L-thyroxine 3. Which of the following conditions will present with a reduced radioactive iodine uptakeIodine-induced thyrotoxicosisPainless thyroiditisAll of the above will result in a reduced uptake of radioactive iodinePost-partum thyroiditisAmiodarone-induced thyrotoxicosis 4. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroxine therapy needs to be discontinuedThyroxine requirements decrease due to transient hyperthyroidism of pregnancyContinue the same dose of L-thyroxineThyroid hormone free levels increase during pregnancyNone of the above statements is correct 5. Which is the best indicator of thyroxine abuse?TSH levelRadioactive Iodine uptakeUltrasound of the thyroid Anti-thyroid peroxidase levelThyroglobulin level 6. Which of the following conditions does not usually result in hypothyrodism?Postpartum thyroiditisUse of radioactive iodine for the treatment of Grave’s diseaseAll of the above conditions may result in hypothyroidismAutoimmune thyroiditisSubacute granulomatous thyroiditis 7. In Grave’s diseaseThyroid Stimulating Immunoglobulins (TSI) are present in serumThe radioiodine uptake is lowThe free thyroid is lowThe thyroid gland shows nodular “hot” nodule 8. Which of the following statements regarding Euthyroid sick syndrome is correctResults in an increase in the peripheral conversion of T4 to T3Causes a marked elevation of TSH levelsThe levels of Free T4 are normal in moderate illnessAnti-thyroglobulin is present in high concentrations 9. In the presence of a TSH secreting pituitary tumorFree T3 increasesHypothyroidism results due to hypothalamic suppression effectThyroglobulin decreasesThe radioactive iodine uptake decreasesFree T4 decreases 10. Which of the following statements regarding the biological effects of thyroid hormone is correct?The thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsNone of the above statements is correctThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormone Loading... Share this:TwitterWhatsAppFacebookEmailPrintLinkedIn Related