PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following statements regarding the biological effects of thyroid hormone is correct?A cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesNone of the above statements is correct 2. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroid hormone free levels increase during pregnancyThyroxine therapy needs to be discontinuedContinue the same dose of L-thyroxineNone of the above statements is correctThyroxine requirements decrease due to transient hyperthyroidism of pregnancy 3. Which is the best indicator of thyroxine abuse?Ultrasound of the thyroid Thyroglobulin level Radioactive Iodine uptakeTSH levelAnti-thyroid peroxidase level 4. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Measure the T4 concentrationDiscontinue L-thyroxineIncrease the dose of L-thyroxineDecrease the dose of L-thyroxineObservation and thyroid studies at 24 weeks 5. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisIt may present as an enlarging thyroid glandAnti-thyroid peroxidase antibodiesAnti-thyroglobulin antibodiesAntibodies to the TSH receptor 6. Which of the following statements regarding Euthyroid sick syndrome is correctCauses a marked elevation of TSH levelsThe levels of Free T4 are normal in moderate illnessAnti-thyroglobulin is present in high concentrationsResults in an increase in the peripheral conversion of T4 to T3 7. Which of the following conditions does not usually result in hypothyrodism?All of the above conditions may result in hypothyroidismSubacute granulomatous thyroiditisPostpartum thyroiditisAutoimmune thyroiditisUse of radioactive iodine for the treatment of Grave’s disease 8. In the presence of a TSH secreting pituitary tumorFree T4 decreasesFree T3 increasesHypothyroidism results due to hypothalamic suppression effectThyroglobulin decreasesThe radioactive iodine uptake decreases 9. In Grave’s diseaseThe radioiodine uptake is lowThe thyroid gland shows nodular “hot” noduleThyroid Stimulating Immunoglobulins (TSI) are present in serumThe free thyroid is low 10. Which of the following conditions will present with a reduced radioactive iodine uptakeIodine-induced thyrotoxicosisPost-partum thyroiditisPainless thyroiditisAll of the above will result in a reduced uptake of radioactive iodineAmiodarone-induced thyrotoxicosis Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related
