PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following statements regarding the biological effects of thyroid hormone is correct?Their biological effects are mediated by interactions between the hormone and cell membrane receptorsNone of the above statements is correctA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormoneThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptors 2. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAntibodies to the TSH receptorIt may present as an enlarging thyroid glandAnti-thyroglobulin antibodiesAnti-thyroid peroxidase antibodies 3. Which of the following conditions will present with a reduced radioactive iodine uptakeIodine-induced thyrotoxicosisAmiodarone-induced thyrotoxicosisAll of the above will result in a reduced uptake of radioactive iodinePainless thyroiditisPost-partum thyroiditis 4. In Grave’s diseaseThyroid Stimulating Immunoglobulins (TSI) are present in serumThe thyroid gland shows nodular “hot” noduleThe free thyroid is lowThe radioiodine uptake is low 5. Which of the following conditions does not usually result in hypothyrodism?Use of radioactive iodine for the treatment of Grave’s diseaseSubacute granulomatous thyroiditisAll of the above conditions may result in hypothyroidismAutoimmune thyroiditisPostpartum thyroiditis 6. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroxine therapy needs to be discontinuedContinue the same dose of L-thyroxineNone of the above statements is correctThyroid hormone free levels increase during pregnancyThyroxine requirements decrease due to transient hyperthyroidism of pregnancy 7. Which is the best indicator of thyroxine abuse?Anti-thyroid peroxidase levelTSH levelRadioactive Iodine uptakeThyroglobulin level Ultrasound of the thyroid 8. Which of the following statements regarding Euthyroid sick syndrome is correctCauses a marked elevation of TSH levelsAnti-thyroglobulin is present in high concentrationsThe levels of Free T4 are normal in moderate illnessResults in an increase in the peripheral conversion of T4 to T3 9. In the presence of a TSH secreting pituitary tumorThyroglobulin decreasesHypothyroidism results due to hypothalamic suppression effectFree T4 decreasesFree T3 increasesThe radioactive iodine uptake decreases 10. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Increase the dose of L-thyroxineObservation and thyroid studies at 24 weeksDecrease the dose of L-thyroxineDiscontinue L-thyroxineMeasure the T4 concentration Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related
