PathMD Quizes, Clinical, Head & Neck Thyroid October 29, 2017 peferguson Author: Max Llaudes, M.D. & Joshua Bornhorst, Ph.D. Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A 34 year old female with history of hypothyroidism controlled with l-thyroxine comes to the office for her 8-week prenatal check-up. Her vital signs and physical examination are non-contributory. What is the appropriate management of the hypothyroidism in this patient?Observation and thyroid studies at 24 weeksIncrease the dose of L-thyroxineDiscontinue L-thyroxineDecrease the dose of L-thyroxineMeasure the T4 concentration 2. Which of the following statements regarding the management of hypothyroid patients during pregnancy is correct?Thyroxine therapy needs to be discontinuedContinue the same dose of L-thyroxineNone of the above statements is correctThyroxine requirements decrease due to transient hyperthyroidism of pregnancyThyroid hormone free levels increase during pregnancy 3. Which is the best indicator of thyroxine abuse?Anti-thyroid peroxidase levelRadioactive Iodine uptakeThyroglobulin level Ultrasound of the thyroid TSH level 4. Which of the following statements regarding Euthyroid sick syndrome is correctResults in an increase in the peripheral conversion of T4 to T3Anti-thyroglobulin is present in high concentrationsThe levels of Free T4 are normal in moderate illnessCauses a marked elevation of TSH levels 5. Which of the following conditions will present with a reduced radioactive iodine uptakeIodine-induced thyrotoxicosisAll of the above will result in a reduced uptake of radioactive iodineAmiodarone-induced thyrotoxicosisPost-partum thyroiditisPainless thyroiditis 6. Which of the following conditions does not usually result in hypothyrodism?All of the above conditions may result in hypothyroidismUse of radioactive iodine for the treatment of Grave’s diseaseAutoimmune thyroiditisSubacute granulomatous thyroiditisPostpartum thyroiditis 7. In the presence of a TSH secreting pituitary tumorFree T3 increasesThyroglobulin decreasesThe radioactive iodine uptake decreasesHypothyroidism results due to hypothalamic suppression effectFree T4 decreases 8. In Grave’s diseaseThe free thyroid is lowThe radioiodine uptake is lowThyroid Stimulating Immunoglobulins (TSI) are present in serumThe thyroid gland shows nodular “hot” nodule 9. Which of the following statements regarding the biological effects of thyroid hormone is correct?None of the above statements is correctThe thyroid hormone water solubility allows to permeate through the cell membrane and bind intranuclear protein receptorsThe thyroid hormone receptors are free intracellular proteins with high specificity and affinity for thyroid hormone binding sitesTheir biological effects are mediated by interactions between the hormone and cell membrane receptorsA cellular transmembrane tyrosine kinase receptor mediates the biological effects of thyroid hormone 10. Which of the following is not a feature of Autoimmune Hashimoto thyroiditisAnti-thyroid peroxidase antibodiesIt may present as an enlarging thyroid glandAntibodies to the TSH receptorAnti-thyroglobulin antibodies Loading... Share this: Share on X (Opens in new window) X Share on WhatsApp (Opens in new window) WhatsApp Share on Facebook (Opens in new window) Facebook Email a link to a friend (Opens in new window) Email Print (Opens in new window) Print Share on LinkedIn (Opens in new window) LinkedIn Related
