1. A 5 cm mass is removed from a 41 y/o female which is found to have areas of smooth muscle cells, blood vessels, and fat. Special stains for HMB-45 were positive. This lesion is associated with all of the following conditions EXCEPT:

2. A 30 y/o African American male whose mother has sickle cell disease, is found to have a renal mass by CT examination. Which of the following are the most likely histologic features of this mass:

3. The best diagnosis for the renal mass illustrated in the images below is which of the following:

4. The best diagnosis for the renal mass illustrated in the images below is which of the following:

5. An incidental renal lesion <1cm with papillary features and composed of predominantly clear cells is best classified as:

6. According to the AJCC staging manual, all of the following affect the pathological staging of renal cell carcinoma EXCEPT:

7. The best diagnosis for the renal mass illustrated in the images below is which of the following:

8. The image below shows a renal tumor stained with Hale’s Colloidal Iron. The most likely diagnosis is:

9. The best diagnosis for the renal mass illustrated in the images below is which of the following:

10. Which of the following result in the highest stage for a renal cell carcinoma according to the 2002 AJCC staging manual:

11. An 18 y/o Caucasian male is found to have a renal tumor with clear cell RCC histology. It is important to perform cytogenetic analysis on this mass to look for involvement of which of the following chromosomes:

12. This tumor from the kidney illustrated in images below was negative for S-100 and desmin. In other areas of the tumor, RCC marker was focally positive. Which of the following is the best diagnosis?

13. A renal tumor has predominantly clear cells with the highest grade area containing cells with irregular nuclear border (size ~20
m) and nucleoli visible from 10X. Many of the cells are noted to have eccentrically placed nuclei and eosinophilic cytoplasm. The best Fuhrman grade is:

14. Which of the following is most helpful in differentiating chromophobe RCC from an oncocytoma: