PathMD Quizes, Renal Renal Neoplasms – 02 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. An 18 y/o Caucasian male is found to have a renal tumor with clear cell RCC histology. It is important to perform cytogenetic analysis on this mass to look for involvement of which of the following chromosomes:Xp11.2Chromosome 73pChromosome 11p13 None of the above 2. Which of the following is most helpful in differentiating chromophobe RCC from an oncocytoma:PleomorphismGranular cytoplasm BinucleationPerinuclear halos 3. A renal tumor has predominantly clear cells with the highest grade area containing cells with irregular nuclear border (size ~20m) and nucleoli visible from 10X. Many of the cells are noted to have eccentrically placed nuclei and eosinophilic cytoplasm. The best Fuhrman grade is:Fuhrman grade VFuhrman grade IIIFuhrman grade IIFuhrman grade IVFuhrman grade I 4. A 30 y/o African American male whose mother has sickle cell disease, is found to have a renal mass by CT examination. Which of the following are the most likely histologic features of this mass:Clear cells with abundant cytoplasm, irregular nuclei, and a fine network of thin walled vessels surrounding nests of cells. Tubulopapillary architecture of infiltrating cells some with a hobnail like appearance. Tumor cell nuclei are high grade. Tubular Mucinous Spindle cell RCC Reticular / yolk sac-like pattern with focal areas having an adenoid-cystic pattern. Papillary cores filled with foamy macrophages admixed with other areas of tubular and solid architecture. The cytoplasm is acidophilic, and no clear cell component is identified. 5. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Conventional Renal Cell Carcinoma, ChromophobeOncocytomaRenal Cell Carcinoma, PapillaryNone of the above 6. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal Tumor Renal TumorNone of the above Wilm’s tumorRenal cell carcinoma, papillary typeRhabdomyosarcomaMetanephric adenoma 7. A 5 cm mass is removed from a 41 y/o female which is found to have areas of smooth muscle cells, blood vessels, and fat. Special stains for HMB-45 were positive. This lesion is associated with all of the following conditions EXCEPT:von Hippel-Lindau (VHL) syndrome Birt-Hogg-Dube syndrome von Recklinghausen disease Tuberous sclerosis 8. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Conventional OncocytomaRenal Cell Carcinoma, ChromophobeRenal Cell Carcinoma, Papillary None of the above 9. The image below shows a renal tumor stained with Hale’s Colloidal Iron. The most likely diagnosis is: Renal Tumor Hale's Colloidal IronRCC, chromophobe type RCC, papillary type RCC, sarcomatoid type RCC, conventional type Oncocytoma 10. According to the AJCC staging manual, all of the following affect the pathological staging of renal cell carcinoma EXCEPT:Extension into renal sinus fat Renal vein involvement Extension into perinephric fat SizeFuhrman grade 11. This tumor from the kidney illustrated in images below was negative for S-100 and desmin. In other areas of the tumor, RCC marker was focally positive. Which of the following is the best diagnosis? Renal Tumor Renal TumorMetastatic malignant melanoma None of the above RCC, Fuhrman grade IV LeiomyomaRhabdomyosarcoma 12. An incidental renal lesion <1cm with papillary features and composed of predominantly clear cells is best classified as:Renal cell carcinoma, clear cell type Renal cell carcinoma, chromophil typeRenal cell carcinoma, NOSPapillary carcinomaPapillary adenoma 13. Which of the following result in the highest stage for a renal cell carcinoma according to the 2002 AJCC staging manual:Metastasis to one single regional lymph nodeTumor invades beyond Gerota’s fasciaTumor directly invades adrenal gland Tumor grossly extends into the vena cava above the diaphragmTumor grossly invades the wall of the vena cava 14. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Chromophobe Renal Cell Carcinoma, Conventional OncocytomaNone of the above Renal Cell Carcinoma, Papillary Loading...
PathMD Quizes, Renal Renal Neoplasms – 01 October 29, 2017 peferguson Please go to Renal Neoplasms – 01 to view this test
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