PathMD Quizes, Renal Renal Neoplasms – 02 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. A renal tumor has predominantly clear cells with the highest grade area containing cells with irregular nuclear border (size ~20m) and nucleoli visible from 10X. Many of the cells are noted to have eccentrically placed nuclei and eosinophilic cytoplasm. The best Fuhrman grade is:Fuhrman grade VFuhrman grade IVFuhrman grade IFuhrman grade IIIFuhrman grade II 2. A 30 y/o African American male whose mother has sickle cell disease, is found to have a renal mass by CT examination. Which of the following are the most likely histologic features of this mass:Papillary cores filled with foamy macrophages admixed with other areas of tubular and solid architecture. The cytoplasm is acidophilic, and no clear cell component is identified. Tubulopapillary architecture of infiltrating cells some with a hobnail like appearance. Tumor cell nuclei are high grade. Reticular / yolk sac-like pattern with focal areas having an adenoid-cystic pattern. Clear cells with abundant cytoplasm, irregular nuclei, and a fine network of thin walled vessels surrounding nests of cells. Tubular Mucinous Spindle cell RCC 3. The image below shows a renal tumor stained with Hale’s Colloidal Iron. The most likely diagnosis is: Renal Tumor Hale's Colloidal IronRCC, conventional type RCC, sarcomatoid type RCC, chromophobe type OncocytomaRCC, papillary type 4. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Papillary None of the aboveRenal Cell Carcinoma, Conventional OncocytomaRenal Cell Carcinoma, Chromophobe 5. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal Tumor Renal TumorNone of the above Wilm’s tumorRhabdomyosarcomaRenal cell carcinoma, papillary typeMetanephric adenoma 6. An incidental renal lesion <1cm with papillary features and composed of predominantly clear cells is best classified as:Renal cell carcinoma, chromophil typeRenal cell carcinoma, clear cell type Papillary adenoma Renal cell carcinoma, NOSPapillary carcinoma 7. Which of the following result in the highest stage for a renal cell carcinoma according to the 2002 AJCC staging manual:Tumor directly invades adrenal gland Tumor grossly extends into the vena cava above the diaphragmTumor invades beyond Gerota’s fasciaMetastasis to one single regional lymph nodeTumor grossly invades the wall of the vena cava 8. Which of the following is most helpful in differentiating chromophobe RCC from an oncocytoma:BinucleationPerinuclear halosPleomorphismGranular cytoplasm 9. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorOncocytomaRenal Cell Carcinoma, ChromophobeNone of the aboveRenal Cell Carcinoma, PapillaryRenal Cell Carcinoma, Conventional 10. A 5 cm mass is removed from a 41 y/o female which is found to have areas of smooth muscle cells, blood vessels, and fat. Special stains for HMB-45 were positive. This lesion is associated with all of the following conditions EXCEPT:Birt-Hogg-Dube syndrome von Hippel-Lindau (VHL) syndrome von Recklinghausen disease Tuberous sclerosis 11. An 18 y/o Caucasian male is found to have a renal tumor with clear cell RCC histology. It is important to perform cytogenetic analysis on this mass to look for involvement of which of the following chromosomes:3pChromosome 11p13 None of the aboveChromosome 7Xp11.2 12. According to the AJCC staging manual, all of the following affect the pathological staging of renal cell carcinoma EXCEPT:Extension into renal sinus fat Renal vein involvement Extension into perinephric fat Fuhrman grade Size 13. This tumor from the kidney illustrated in images below was negative for S-100 and desmin. In other areas of the tumor, RCC marker was focally positive. Which of the following is the best diagnosis? Renal Tumor Renal TumorLeiomyomaRhabdomyosarcomaMetastatic malignant melanoma RCC, Fuhrman grade IV None of the above 14. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Conventional None of the above Renal Cell Carcinoma, Papillary OncocytomaRenal Cell Carcinoma, Chromophobe Loading...
PathMD Quizes, Renal Renal Neoplasms – 01 October 29, 2017 peferguson Please go to Renal Neoplasms – 01 to view this test
PathMD Quizes, Neuropathology Neuropathology – 01 October 29, 2017 peferguson Please go to Neuropathology – 01 to view this test
PathMD Quizes, GI Pathology GI Pathology – 01 October 29, 2017 peferguson Please go to GI Pathology – 01 to view this test
PathMD Quizes, Clinical Clinical Chemistry – 01 October 29, 2017 peferguson Please go to Clinical Chemistry – 01 to view this test
PathMD Quizes, Clinical Immunology – 01 October 29, 2017 peferguson Please go to Immunology – 01 to view this test
PathMD Quizes, Cytology Cytology – 01 October 29, 2017 peferguson Please go to Cytology – 01 to view this test
PathMD Quizes, Dermatopathology Dermatopathology – 01 October 29, 2017 peferguson Please go to Dermatopathology – 01 to view this test
PathMD Quizes, Clinical Blood Bank – 04 October 29, 2017 peferguson Please go to Blood Bank – 04 to view this test
PathMD Quizes, Clinical Blood Bank – 03 October 29, 2017 peferguson Please go to Blood Bank – 03 to view this test