PathMD Quizes, Renal Renal Neoplasms – 02 October 29, 2017 peferguson Make sure to subscribe to PathMD to stay up to date with new content and features!! 1. Which of the following is most helpful in differentiating chromophobe RCC from an oncocytoma:Granular cytoplasm PleomorphismPerinuclear halosBinucleation 2. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorRenal Cell Carcinoma, Conventional None of the aboveRenal Cell Carcinoma, ChromophobeRenal Cell Carcinoma, PapillaryOncocytoma 3. A 30 y/o African American male whose mother has sickle cell disease, is found to have a renal mass by CT examination. Which of the following are the most likely histologic features of this mass:Clear cells with abundant cytoplasm, irregular nuclei, and a fine network of thin walled vessels surrounding nests of cells. Papillary cores filled with foamy macrophages admixed with other areas of tubular and solid architecture. The cytoplasm is acidophilic, and no clear cell component is identified. Tubulopapillary architecture of infiltrating cells some with a hobnail like appearance. Tumor cell nuclei are high grade. Tubular Mucinous Spindle cell RCC Reticular / yolk sac-like pattern with focal areas having an adenoid-cystic pattern. 4. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal Tumor Renal TumorRenal cell carcinoma, papillary typeMetanephric adenoma Wilm’s tumorNone of the above Rhabdomyosarcoma 5. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorNone of the aboveRenal Cell Carcinoma, ChromophobeOncocytomaRenal Cell Carcinoma, Conventional Renal Cell Carcinoma, Papillary 6. An 18 y/o Caucasian male is found to have a renal tumor with clear cell RCC histology. It is important to perform cytogenetic analysis on this mass to look for involvement of which of the following chromosomes:Xp11.2None of the aboveChromosome 11p13 Chromosome 73p 7. This tumor from the kidney illustrated in images below was negative for S-100 and desmin. In other areas of the tumor, RCC marker was focally positive. Which of the following is the best diagnosis? Renal Tumor Renal TumorLeiomyomaNone of the above Metastatic malignant melanoma RCC, Fuhrman grade IV Rhabdomyosarcoma 8. A 5 cm mass is removed from a 41 y/o female which is found to have areas of smooth muscle cells, blood vessels, and fat. Special stains for HMB-45 were positive. This lesion is associated with all of the following conditions EXCEPT:Birt-Hogg-Dube syndrome Tuberous sclerosis von Hippel-Lindau (VHL) syndrome von Recklinghausen disease 9. Which of the following result in the highest stage for a renal cell carcinoma according to the 2002 AJCC staging manual:Tumor grossly invades the wall of the vena cava Tumor grossly extends into the vena cava above the diaphragmTumor directly invades adrenal gland Tumor invades beyond Gerota’s fasciaMetastasis to one single regional lymph node 10. An incidental renal lesion <1cm with papillary features and composed of predominantly clear cells is best classified as:Papillary carcinomaRenal cell carcinoma, clear cell type Renal cell carcinoma, NOSRenal cell carcinoma, chromophil typePapillary adenoma 11. The image below shows a renal tumor stained with Hale’s Colloidal Iron. The most likely diagnosis is: Renal Tumor Hale's Colloidal IronRCC, chromophobe type RCC, sarcomatoid type RCC, papillary type OncocytomaRCC, conventional type 12. A renal tumor has predominantly clear cells with the highest grade area containing cells with irregular nuclear border (size ~20m) and nucleoli visible from 10X. Many of the cells are noted to have eccentrically placed nuclei and eosinophilic cytoplasm. The best Fuhrman grade is:Fuhrman grade IIFuhrman grade IIIFuhrman grade IVFuhrman grade IFuhrman grade V 13. According to the AJCC staging manual, all of the following affect the pathological staging of renal cell carcinoma EXCEPT:SizeFuhrman grade Extension into renal sinus fat Extension into perinephric fat Renal vein involvement 14. The best diagnosis for the renal mass illustrated in the images below is which of the following: Renal Tumor Renal Tumor Renal TumorOncocytomaRenal Cell Carcinoma, Conventional None of the above Renal Cell Carcinoma, Chromophobe Renal Cell Carcinoma, Papillary Loading...
PathMD Quizes, Renal Renal Neoplasms – 01 October 29, 2017 peferguson Please go to Renal Neoplasms – 01 to view this test
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